Figure 4: Mallory's trichrome stain and F4/80 immunohistochemistry in the kidney. GW501516 decreases F4/80, a macrophage marker, immunostaining and immunodensity. A: Mallory's trichrome stain. Arrows indicate collagen deposition around glomeruli. B: F4/80 immunohistochemistry labelling. Arrows indicate macrophage infiltration around glomeruli.